free shipping on all domestic orders weighing up to 1lb

What is L-Histidine Used for? Benefits & More

What is L-Histidine Used for? Benefits & More

Posted by Prolab Nutrition on 21st Sep 2022

What is L-Histidine?

L-histidine is an essential amino acid that must be obtained through dietary sources and supplements. It is also one of the 23 proteinogenic amino acids, which means it can be used to synthesize proteins. L-histidine is a precursor for histamine, which plays an essential role in localized immune responses. Histamine is important because it helps the body tissues release substances that protect against pathogens. It also helps to repair damaged tissue. L-histidine is also the precursor for other important organic compounds such as anserine and carnosine. The German physician Albrecht Kossel discovered histidine in 1896. At first, histidine was thought to be an essential amino acid only in infants, but a 1975 study showed that adults need it too. Although humans can biosynthesize small amounts of L-histidine, this quantity falls short of what's needed nutritionally. It is recommended to  supplement your L-histidine intake.

Key Signs You Need L-Histidine

As you age, it's not uncommon to experience joint stiffness and discomfort. This is often due to a lack of L-histidine, which is an essential amino acid for healthy joints. A low L-histidine level can also cause nerve deafness and an imbalance of intestinal flora. If you're experiencing any of these symptoms, L-histidine supplements may be right for you. Additionally, oxidative stress can cause visible signs of aging, including wrinkles and fine lines. If you're concerned about the effects of aging, L-histidine may help to reduce the appearance of these signs.  Prolab Nutrition offers Beta Alanine with 300mg of L-Histidine!

Beta Alanine Banner

Beta Alanine Paired With L-Histidine

Histidine is an essential amino acid that plays a role in a variety of important biological processes. The beneficial effects of histidine may occur through the metabolism of histidine to carnosine or histamine, two metabolic products that have well-documented roles in allergic responses, gastric secretions, cognitive function, and cardiometabolic health. Histidine is also involved in the regulation of oxidative stress, an important factor in many chronic diseases. Together with alanine, histidine forms the dipeptide carnosine (β-alanyl-L-histidine), which is highly concentrated in muscle (skeletal muscle and cardiac) and brain tissues. Carnosine has been shown to have powerful antioxidant and anti-inflammatory properties, making it a potentially valuable tool in the prevention and treatment of many chronic diseases.


Anyone who has lifted weights before knows the feeling of muscles burning, known as lactic acid buildup. This occurs when your muscles produce lactic acid faster than it can be removed. As lactic acid builds up, it causes discomfort and fatigue, making it difficult to continue working out. Beta-alanine is an amino acid that helps to delay the accumulation of lactic acid, allowing you to work out for longer periods of time. By taking beta-alanine before a workout, you can improve your endurance and make the most of your time at the gym. In addition, beta-alanine can help you to build more muscle mass by enabling you to do more sets and reps. For these reasons, beta-alanine is a valuable supplement for anyone who wants to improve their workout performance.